Medically reviewed by Alan Carter, Pharm.D. — created by Jill Seladi-Schulman, Ph.D. Top top December 19, 2018

Share ~ above Pinterest
Acetaminophen (Tylenol) and ibuprofen (Advil) room both over-the-counter (OTC) medicines that have the right to be supplied to relax pain.

You are watching: Can you mix nyquil and advil

These medicines are two different species of pain relievers. Acetaminophen, sometimes detailed as APAP, is its own type, if ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID).

Generally, it’s safe to take acetaminophen and also ibuprofen together, but you’ll want to salary close attention to how much you take it of each medication.

The crucial to safely taking acetaminophen and also ibuprofen is knowing exactly how much you’re acquisition at a time and how often.

Acetaminophen dosage

The maximum for sure dosage of paracetamol for anyone end the age of 12 is 4,000 milligrams (mg) every day. Yet even this lot can injury some people’s livers, therefore aim for no much more than 3,000 mg per day.

For kids under the period of 12, it’s finest to examine with their healthcare provider to identify the safest sheep for your body weight.

Keep in mental that plenty of OTC medications contain acetaminophen in a variety of doses, usually 325 mg, 500 mg, or 650 mg.

Some instances of brand-name OTC drugs that may contain acetaminophen include:


Remember: when looking at labels, you might also see acetaminophen provided as APAP.

Ibuprofen dosage

Avoid taking much more that 1,200 mg of ibufrofen in a single day. OTC ibuprofen is often found in 200 mg pills. This translates to 6 pills a day. Still, girlfriend should always verify how much is in every pill.

Again, because that children, it’s finest to asking their health care provider about the safest sheep for your weight.

See more: Song From University Of Phoenix Commercial, University Of Phoenix: We Can Do It

If you have prescription-strength ibuprofen, talk to her prescriber before mixing that with any type of other medications, including acetaminophen.


The recommended borders for adults and also children end 12 are:

3,000 mg per day that acetaminophen1,200 mg every day of ibuprofen

For youngsters under the period of 12, call their healthcare provider or describe the product label for dosage guidelines.

You deserve to take ibuprofen and acetaminophen at the exact same time. Just make sure to not take an ext than the recommended dose.

Some people experience some stomach or ab pain once taking the two medicines together. In this case, it’s much better to alternative when you take each medication.

For example, you can take ibufrofen first, adhered to by acetaminophen four hours later, and also then repeat this process as needed.

You could also alternate days. Because that example, if you take ibuprofen top top Monday, take acetaminophen on Tuesday and also so on.